Are you in need of the best drug quality, full compliance and data integrity?
Anton Paar offers a wide range of scientific and analytical instrumentation used in R&D, production, process control, and quality control in the pharmaceutical, cosmetics, and biotech industries and in life sciences. These measurement solutions include refractometry, polarimetry, density, particle analysis, microwave synthesis and digestion, rheometry, and many others.
Additionally, we offer a comprehensive pharmaceutical compliance package, including 21 CFR Part 11 compliance, and installation services. This makes it easy and cost-efficient to incorporate Anton Paar instruments into your regulated environment. More than 1000 instruments and instrument combinations have been successfully qualified with our Pharma Qualification Package and have subsequently passed numerous audits.
Anton Paar Products
Abbemat Heavy Duty Line
Abbemat MW Multiwavelengths Refractometer
Abbemat Performance and Performance Plus Line
Abel Flash Point Tester: ABA 4
Automatic Dilution and Dosage System: DDS
Automatic Process Polarimeter: Propol
Ball Mill BM500
Benchtop Raman spectrometers: Cora 7X00
Cryo & Humidity Chamber: CHC plus⁺
Density and sound velocity meter: DSA 5000 M
Density meter: DMA™ 1001
Density meter: DMA™ 501
Density meter: DMA™ 4100 M
Density meter: DMA™ 4500 M
Density meter: DMA™ 5000 M
Dynamic shear rheometer measuring head: DSR 502
HTR Compact: Rheometer autosampler for high sample throughput
HTR: Rheometer automation for high sample throughput and complex sample handling
HTX: Measurement of viscosity, density, concentration of liquids, highly automated and expandable
Handheld Raman spectrometer: Cora 100
Handheld density meter: DMA 35 Basic
High Pressure Digestion: HPA-S High Pressure Asher
High-precision thermometers: MKT 50 and MKT 10
L-Com 5500: Combined density and sound velocity sensor
L-Dens 3300 density sensor
L-Rix 5000/5100/5200 inline refractometer
Low-Temperature Chamber: TTK 600
MCP 100 Modular Circular Polarimeter
MCP 150 Modular Compact Polarimeter
Micro Combi Tester (MCT³)
Micro Scratch Tester (MST³)
Microindentation Tester (MHT³)
Microwave Digestion System: Multiwave GO
Microwave Digestion and Extraction: Rotor 16SOLV HF100
Microwave Digestion and Extraction: Rotor 16SOLV MF100
Microwave Digestion: Rotor 16HF100
Microwave Digestion: Rotor 16MF100
Microwave Evaporation: Rotor 8EVAP
Microwave Reaction System: Multiwave PRO
Microwave Synthesis in the Kilolab: Masterwave BTR
Microwave Synthesis: Monowave 400/200
Microwave-assisted Drying: Rotor 1DRY
Modular Circular Polarimeter: MCP 5100/5300/5500
Monowave 450: Automated Microwave-assisted Extraction
Multiparameter Analysis: Modulyzer
Nanoindentation Tester (NHT³)
PC-controllable Alignment Stage
Penetrometer: PNR 12
Pensky-Martens flash point tester: PMA 5
Portable benchtop Raman spectrometers: Cora 5X00
Portable density meter: DMA 35
Pressure Sensor Accessory
Revetest® Scratch Tester (RST³)
Rheometer: MCR 102, MCR 302, MCR 502
Rheometer: MCR 72 and MCR 92
Rolling-ball viscometer Lovis 2000 M/ME
Rotational Rheometer: RheolabQC
Rotational Viscometer ViscoQC 100
Rotational Viscometer ViscoQC 300
Routine SAXS/WAXS/BIOSAXS analysis: SAXSpace
SAXS/WAXS/GISAXS laboratory beamline: SAXSpoint 2.0
Sample changer: Xsample 320
Sample changer: Xsample 530
Snap 51 Portable Alcohol Meter for Distilled Spirits
Software for particle analysis: Kalliope™
TRB³: Pin-on-disk tribometer
Tag Flash Point Tester: TAG 4
Ultra Nanoindentation Tester (UNHT³)
Vacuum Tribometer (VTHT / VTRB)
p/T Sensor Accessory
pH ME Beverage Measuring Module and pH ME Measuring Module
Anton Paar Applications
Application PNR 12: Consistency Measurement According to the European Pharmacopoeia 2.9.9 and the U.S. Pharmacopeia (USP)
Suitable for products like white or yellow petrolatum (vaselinum album and flavum), ointment, wax and carboxymethylcellulose sodium paste.
Application PNR 12: Consistency of Carboxymethylcellulose Sodium Paste
The penetrometer PNR 12 allows a rating of the plasticity or consistency of carboxymethylcellulose sodium paste containing products.
Application PNR 12: Consistency of Pharmaceutical Products
The Penetrometer PNR 12 is suitable for consistency measurements required in the pharmaceutical industry. Various test kits are available for different pharmaceutical products and standards like the official WHO method European Pharmacopoeia 2.
Applications of nanoindentation in biology and medicine
Nanoindentation for biological materials
Continuous Monitoring of Hydrogen Peroxide
Relevant for detergents/cleaners, descaling agent, beverages, food industry, pharmaceuticals, personal care
Correlating Viscosity and Particle Size Parameters determined by Small Angle X-Ray Scattering Studies of concentrated MAb Solutions
Monoclonal antibodies (MAb) solutions are a major class of biopharmaceuticals with various applications. However, challenges like a high viscosity at the required MAb concentrations need to be addressed at an early development stage.
Cross-selling with MCP | Reliable Partner for Pharmaceutical Industries
The pharmaceutical market shows a strong demand for efficient and improved synthesis methods of active components (APIs) as well as for effective analysis methods.
Determination of Camphor by Polarimetry
Camphor is naturally produced by trees of the laurel family. It has a strong aromatic odour and is used for various medical and non-medical applications.
Determination of Glucosamine via Polarimetry
Glucosamine is used as a joint supplement for the treatment of arthralgia and osteoarthritis. In order to have high-quality products the optical rotation of glucosamine needs to be analyzed via polarimetry.
Determination of the Enantiomeric Purity of Dextromethorphan Hydrobromide
Dextromethorphan, the dextrorotatory enantiomer of methorphan, serves as an antitussive drug. According to the US pharmacopoeia, the optical rotation of dextromethorphan hydrobromide has to be measured at a wavelength of 325 nm whereas the EU pharmacopoeia
Fast Structure Analysis of Pharmaceutical Excipients by SWAXS for Product Quality Control
The nanostructure of pharmaceutical excipients used as taste masking agents was rapidly determined for quick quality control with the SAXSpace system.
Glycerol is used in various industries as a moisturizer, a thickener, as antifreeze or as a precursor for explosives. Its quality as well as its concentration in solution can be determined by using refractometry.
Gold nanoparticles: Size matters, and so does stability
Gold nanoparticles are now used in many fields, from medicine to electronics, but each application has specific particle-size and stability requirements. Gold nanoparticles can be easily monitored with the Litesizer™ 500.
Identifying three different particle sizes in one sample with DLS
Particle suspensions often contain more than one size of particle. However, many particle analyzers cannot resolve particle mixtures, instead they detect an average of all sizes. The Litesizer™ 500 can detect three sizes in one sample.
Improve Digestion Quality and Save Money – Microwave Digestion rules out Open Digestion
Reliable elemental analysis results need robust sample preparation to destroy sample matrices or to separate matrix from analytes. The sample preparation step is by far the most error-prone and critical step of the analytical procedure.
Intelligent Quartz Control Plates for Polarimetric Calibration and Adjustment
Modern polarimeters are calibrated or adjusted with intelligent quartz control plates that do not require manual data entry in order to ensure data traceability.
L-Rix 510: Determination of Concentration on Producing Dialysis Products
L-Rix 510 – Enjoy the simplicity of refractive index measurements without maintenance or adjustments.
Mesoporous thin films - Investigating the structure of multi-layered films by GISAXS
Single- and double-layered mesoporous thin films have been analyzed by GISAXS for their structural properties using the SAXSpoint system.
Nanoparticles for Ceramics: Size, Stability & pH
In nanoparticle suspensions that will be used in ceramics, particle size and stability are of vital importance. Suspension stability is essential to ensure that the particles to stay in suspension, and maintain constant particle size.
Nanotribological properties of Diamond like carbon thin flexible films on ACM rubber
Pharma, Cosmetics - Determining the Rheological Properties of Pharmaceutical Products
The rheological characterisation of microemulsions with the Rotational Rheometer RheolabQC gives essential information about their properties and the customer’s evaluation of the end product.
Polarimeters for Processing Applications
The Propol process polarimeter is ideal for process applications on chiral compounds such as sugars and pharmaceuticals. It is designed to be placed inline or in bypass allowing continuous measurements.
Polarimetric Determination of Lactose Content in High Lactose Dairy Products
The quality of milk and milk powders depends, among others, on the lactose content. The lactose needs to be extracted from dairy products having high lactose content (e.g. milk and milk powders) before using the polarimeter for concentration determination.
Quality Control in Drugs
Polarimeters are essential in drug quality control to ensure the enantiomeric purity and therefore efficacy of pharmaceutical drugs.
Quality Control of Saline Solution
Abbemat refractometers from Anton Paar are valuable instruments for the precise analysis of concentration and purity of saline solutions.
Quality control of pharmaceutical excipients during storage and processing
The structure of pharmaceutical excipients as a function of storage time and temperature was analyzed by small- and wide-angle X-ray scattering using the SAXSpace system.
Refractive Index of Essential Oils
The refractive index of essential oils is a quickly measured, easily generated quality parameter. Moreover, it helps to differentiate between different essential oils.
Refractometric analysis of fats and oils
The refractive index or butyro value of animal and vegetable fats and oils is a quickly measured, easily generated quality parameter value. Moreover, it helps to differentiate between different fats, such as butter and margarine.
SAXSpoint with MetalJet Source
SAXSpoint now integrates the high-brightness MetalJet X-ray source enabling ultra-fast SAXS measurements in the laboratory.
Size and shape of gold nanoparticles in toluene via SAXS
A solution of colloidal gold nanoparticles was characterized for size and shape by the SAXSpace system.
Spherical Nanoindentation of Polyacrylamide Hydrogels using the Bioindenter (BHT)
Starch Decomposition with Subsequent Polarimetric Content Determination
This method is suitable for the determination of starch and high molecular weight starch degradation products in food or feedstuffs in compliance with the EC Commission Directive 86/174/EEC and Council Directive 96/25/EC. Please note that this method requi
Targeting Alzheimer’s disease - studying the fibril structure of the Amyloid beta protein on a laboratory system
The fibril structure of Amyloid beta has been studied with the SAXSpoint 2.0 system.
Temperature-dependent GISAXS studies on thin films
The temperature-induced decomposition of a thin film structure has been studied using the SAXSpoint system with the new temperature-controlled GISAXS stage.
The Ultra Nanoindentation Tester: New generation of thermal drift free indentation
The influence of Surface Roughness on Instrumented Indentation Testing (IIT)
Compliance and data integrity
Our instruments comply with the pharmacopoeia methods stated in the US Pharmacopeia (USP), European Pharmacopoeia (Ph.Eur.) and many other national regulations. The high end instruments and combined instrument setups can be connected to LIMS, the network or USB for easy and secure data transfer. Software features like e.g. audit trail, electronic signature, user management, backup functions and data export for full data integrity minimize the risk of non-compliance. The high accuracy and reliability of our instruments guarantee the lowest possible error ratio. Our requalification service also supports you in case of yearly requalification, change of the instrument’s location, and many other cases.
Pharma Qualification Package and installation service
With Anton Paar’s qualification service your new instrument is ready for routine operation within 1 to 3 working days, reducing the work required by your in-house personnel. More than 1000 instruments and instrument combinations have been successfully qualified with our Pharma Qualification Packages.
To support your compliance and traceability needs, Anton Paar offers more than 40 instrument-specific qualification packages as well as qualified installation support. Pharma Qualification Packages by Anton Paar include much more than the standard IQ/OQ and are prepared individually for every instrument and customer. They include all required documents for complying with relevant regulations like USP 1058, GAMP 5, GMP, and 21 CFR Part 11.
Profit from the expert’s knowledge: End user training
Anton Paar offers end user training to maximize your benefit from our instruments. We strive to share our broad knowledge about instruments, technologies, handling and applications. Our sales and service representatives are highly qualified, trained and certified by the comprehensive Anton Paar internal trainings program.
Multiple parameter measurement for fast and reliable results
Numerous samples such as gels, creams, infusions, APIs, blood samples, essential oils, proteins, and polymers can be investigated by measuring various parameters such as density, viscosity, refractive index, polarimetry, and turbidity. Choose from our comprehensive product portfolio. Individual instruments can be combined easily to make multiparameter measurement systems. Innovative products for high sample throughput using low sample volume or sample recovery are an essential part of our portfolio. Laboratory automation and inline/at-line solutions are provided. These meet pharmaceutical requirements, ranging from R&D to quality control.
You are not alone: Global on-site service
We offer on-site service by highly experienced support staff via a vast network of representatives from 30 subsidiaries and 60 distribution partners. Experts on call and service programs ensure peace of mind, guarantee the highest quality operation throughout an instrument’s lifespan, and reduce standby times. Our different service programs are designed to match individual needs, from the recommended preventive maintenance programs to full repair coverage. In case of a repair, instrument location change, software update or any other reason, our pharma requalification package guarantees that your instrument qualification is up to date and your instrument is compliant throughout its working life.