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Multiparameter Analyzing System:
Modulyzer Pharma

  • Fast measurement of multiple parameters – 1 sample, 1 filling
  • Guaranteed data integrity and traceability
  • Full compliance to Pharmacopeia regulations
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Complex measuring tasks meet modular multiparameter measuring system: Modulyzer Pharma combines a density meter, a refractometer, and a rolling ball viscometer with a versatile sample changer. It opens up the possibility to get more parameters from one sample filling. The system is compliant to regulations and configurable to your needs. Comprehensive software features for the requirements of the pharmaceutical industry help to avoid measuring errors, to track every action with the instrument, and to keep the data safe.

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Key features

Multiple parameters from one sample – customized to your needs

Multiple parameters from one sample – customized to your needs

Density, refractive index, and viscosity from one sample and one filling – this is the power of Modulyzer Pharma. The highly flexible measuring setup can be adapted to measure only the parameters needed. The complete setup can be further extended with additional modules for optical rotation or turbidity. This can save you up to 80 % of your valuable working time in the lab compared to manual methods.

Full compliance to Pharmacopeia regulations

Full compliance to Pharmacopeia regulations

Modulyzer Pharma combines a state-of-the-art density meter, a refractometer, a rolling-ball viscometer and a sample changer in one system. The measuring technology of these modules conforms to all major pharmacopeia. This means full compliance, allowing you to focus on the results instead of the technology.

(Pharmacopeia reference for density meters: USP <841>|Ph. Eu. 2.2.5|JP 17 2.56|ChP 2020 (Vol IV) 0601; for refractometers: USP <831>|Ph. Eu. 2.2.6| ChP 2020 (Vol IV) 0622 | JP 17 2.45; for rolling ball viscometers: USP <913>|Ph. EU. 2.2.49)

Full traceability for every step

Full traceability for every step

The “what, when, why, and who” of every step with your instruments need to be documented according to GMP regulations and for later audit purposes. In the Modulyzer Pharma’s software, measurements, checks, adjustments and changes of instrument settings, users, and methods are tracked in a comprehensive audit trail. Fully customizable user and role management with individually configurable permissions and password rules according to your requirements allow for a clear attribution of any action to a specific user. Thus, you maintain full overview and benefit from simple review possibilities.

Keep your data safe – guaranteed integrity and traceability

Keep your data safe – guaranteed integrity and traceability

Keeping data and accompanying meta-data from your laboratory safe over the retention time is a critical point in your product’s life cycle. Embedded software features in the modular system from Anton Paar like the advanced data integrity mode help you avoid loss of data.

The software package AP Connect Pharma is the solution to connect your instruments, collect data and audit trails, and manage them accordingly. It allows for user-centered data review and approval processes, which can even be remote. The program offers simple search and filter options for the entries and also automatic export to connected LIMS systems. Needless to say, the electronic signature is fully 21 CFR part 11 compliant. Since you don’t have to worry about data availability and accessibility, you can dedicate your time to data quality and deriving the right decisions.

Minimal time to get ready for operation

Minimal time to get ready for operation

Modulyzer Pharma offers straightforward and fast set up for operation. System installation, user and applicative training by well-trained Anton Paar staff together with the available pharma qualification packages and qualification services by specialists help you to simplify your own qualification process and to save weeks to even months of time.

Automation at your fingertips – adjust the level of individuality you need

Automation at your fingertips – adjust the level of individuality you need

High sample throughput and different measurement requirements can be challenging. Modulyzer Pharma is equipped with a versatile sample changer. Not only does it allow reproducible and repeatable filling of even difficult samples (e.g. higher viscosity, hazardous components) into the measuring modules, but it can also properly and traceably clean and check them afterwards. This frees up valuable resources for other tasks in your laboratory.

Technical specifications

Measuring range Accuracy Repeatability
DMA™ 4500 M Density 0 g/cm³ to 3 g/cm³ 0.00005 g/cm³ 0.000005 g/cm³
Temperature 0 °C to 100 °C 0.03 °C 0.01 °C
LOVIS 2000 ME Viscosity 0.3 mPa.s to 10,000 mPa.s up to 0.5 %*,** up to 0.1 %*
Temperature + 5 °C to 100 °C 0.005 °C 0.02 °C
Abbemat 300 Refractive index 1.26 nD to 1.72 nD ±0.0001** -
Temperature 4 °C to 85 °C ±0.002 °C*** ±0.05 °C***
Xsample 530 Viscosity 12,000 mPa·s with internal air pump
36,000 mPa·s with external compressed air

* depends on sample type and measuring settings, without changing the ball
**for the range in which the calibration constant was determined, not including uncertainty of reference standards
*** Valid at refractometric standard conditions (T = 20 °C, λ = 589 nm, ambient temperature = 23 °C)

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