生物技术样品

深入研究样品特性以了解其复杂的过程和相互作用

在应用免疫学、分子工程和基因工程等领域,获取材料特性信息有时很简单,比如测量不同温度下物质的浓度,有时很复杂,比如表征纳米结构及其在不同条件下的特性。安东帕勇于探索需要测量技术和分析方法的领域。

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Anton Paar 产品

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autosorb iQ 系列

HTR:用于高样品处理量和复杂样品处理的流变仪自动化

HTX:测量液体的黏度、密度、浓度,高度自动化和可扩展

L-Rix 5000/5100/5200 在线折光仪

Litesizer 100

Litesizer 500

MCP 100 高精度智能旋光仪

MCP 150

MCP 150 高精度智能旋光仪

Monowave 450: 全自动微波萃取系统

Oxy 510 在线溶氧传感器

pH ME 饮料测量模块和 pH ME 测量模块

Revetest® 大载荷划痕测试仪 (RST³)

SAXSpace 仪器

SAXS/WAXS/BIOSAXS 常规分析:SAXSpace

SAXS/WAXS/GISAXS/RheoSAXS 实验室光束线装置SAXSpoint 5.0

Cryo 和潮湿箱 CHC plus+ 是多用途 CHC Cryo 和潮湿箱与先进湿度 (RH) 发生器的独特组合,使用 X 射线衍射分析材料中湿敏和/或随温度变化的结构变化。

低温和潮湿箱:CHC plus⁺

低温室:TTK 600

Cora 5X00 Raman Spectrometer

便携台式拉曼光谱仪:Cora 5X00

便携式密度计:DMA 35

动态剪切流变仪测量头:DSR 502

Cora 7X00 Raman Spectrometer with Fiber-optic probe

台式拉曼光谱仪:Cora 7X00

安东帕生物压痕测试仪 (UNHT³ Bio)

依托革命性的创新技术,全新 Masterwave BTR 台式反应器让微波合成首次走进千克实验室。实验室的效率大幅提升,每天可合成多达数千克的化合品。此台式反应器配备由磁场驱动的桨式搅拌器,可针对各个样品分别提供独立的搅拌策略。Masterwave BTR 采用了最新的传感器温度测量技术,可以提供从任何小型微波器件直接转移到新的千克实验室所需的温度精度。

实验室中千克的微波合成:Masterwave BTR

密度与声速仪:DSA 5000 M

密度计:DMA 1001

密度计:DMA 4100 M

密度计:DMA 4500 M

密度计:DMA 5000 M

常规固体表面分析的电动分析仪:SurPASS™ 3 Eco

微波合成系统:Monowave 400/200

微波消解系统:Multiwave GO Plus

酸消解转子 16HF100 具有 16 个高压容器,设计用于高样品通量和有效输送。

微波消解:转子 16HF100

微米划痕测试仪 (MST³)

微米压痕仪 (MHT³)

微观组合测试仪 (MCT³)

手持式密度计:DMA 35 Basic

手持式拉曼光谱仪:Cora 100

Abbemat 高性能和高端模块化

折光仪:Abbemat 高性能和高端模块化系列

Abbemat Heavy Duty

折光仪:Abbemat 高端多功能系列

已安装 T 探头的俯视图,带 Multiwave PRO 的转子 8N。

插入式温度传感器

The RheolabQC is the quality control rheometer from Anton Paar. RheolabQC with temperature device C-PTD 180/AIR/QC and with Flexible Cup Holder.

旋转流变仪:RheolabQC

流变仪:MCR 102、MCR 302、MCR 502

流变仪:MCR 72 和 MCR 92

球/销盘式摩擦磨损试验机:TRB³

球磨机 BM 500

用于四圆测角仪的圆顶冷却台:DCS 500

电动固体表面分析仪:SurPASS™ 3

电脑控制的对准台

High Temperature Vacuum Tribometer

真空摩擦计 (VTHT / VTRB)

粒度分析软件:Kalliope™

紧凑型 HTR:流变仪 - 用于高样品处理量的自动进样器

纳米划痕测试仪:NST³

纳米压痕测试仪:NHT³

自动在线旋光仪:Propol

自动在线旋光仪:Propol

自动稀释配液系统:DDS

自动稀释和配液系统:DDS

落球式黏度计 Lovis 2000 M/ME

超纳米压痕测试仪:UNHT³

高精度温度计:MKT 50 和 MKT 10

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Anton Paar 应用

Lactose Purity According to Pharmacopoeia

Lactose Purity According to Pharmacopoeia

The US and the European pharmacopoeias demand the analysis of the purity of lactose monohydrate polarimetrically. Determining the specific rotation with an MCP polarimeter from Anton Paar ensures high-quality products.

Glycerol

Glycerol

Glycerol is used in various industries as a moisturizer, a thickener, as antifreeze or as a precursor for explosives. Its quality as well as its concentration in solution can be determined by using refractometry.

Quality Control in Drugs

Quality Control in Drugs

Polarimeters are essential in drug quality control to ensure the enantiomeric purity and therefore efficacy of pharmaceutical drugs.

Quality Control of Saline Solution

Quality Control of Saline Solution

Abbemat refractometers from Anton Paar are valuable instruments for the precise analysis of concentration and purity of saline solutions.

Improve Digestion Quality and Save Money – Microwave Digestion rules out Open Digestion

Improve Digestion Quality and Save Money – Microwave Digestion rules out Open Digestion

Reliable elemental analysis results need robust sample preparation to destroy sample matrices or to separate matrix from analytes. The sample preparation step is by far the most error-prone and critical step of the analytical procedure.

In-Situ observation of the scratch/indentation true contact area to provide analysis without being model-dependent

In-Situ observation of the scratch/indentation true contact area to provide analysis without being model-dependent

Nanoindentation approach to mechanical testing of extremely soft materials

Nanoindentation approach to mechanical testing of extremely soft materials

Nanotribological properties of Diamond like carbon thin flexible films on ACM rubber

Nanotribological properties of Diamond like carbon thin flexible films on ACM rubber

Review of Indenter Materials for High Temperature Nanoindentation

Review of Indenter Materials for High Temperature Nanoindentation

Spherical Nanoindentation of Polyacrylamide Hydrogels using the Bioindenter (BHT)

Spherical Nanoindentation of Polyacrylamide Hydrogels using the Bioindenter (BHT)

The Ultra Nanoindentation Tester: New generation of thermal drift free indentation

The Ultra Nanoindentation Tester: New generation of thermal drift free indentation

Gold nanoparticles: Size matters, and so does stability

Gold nanoparticles: Size matters, and so does stability

Gold nanoparticles are now used in many fields, from medicine to electronics, but each application has specific particle-size and stability requirements. Gold nanoparticles can be easily monitored with the Litesizer™ 500.

Applications of nanoindentation in biology and medicine

Applications of nanoindentation in biology and medicine

Nanoindentation for biological materials

Intrinsic bone tissue quality is altered in osteo-porosis and selectively influenced by its treatments

Intrinsic bone tissue quality is altered in osteo-porosis and selectively influenced by its treatments

Nanoindentation for bone and mineral materials

Identifying three different particle sizes in one sample with DLS

Identifying three different particle sizes in one sample with DLS

Particle suspensions often contain more than one size of particle. However, many particle analyzers cannot resolve particle mixtures, instead they detect an average of all sizes. The Litesizer™ 500 can detect three sizes in one sample.

Nanoparticles for Ceramics: Size, Stability & pH

Nanoparticles for Ceramics: Size, Stability & pH

In nanoparticle suspensions that will be used in ceramics, particle size and stability are of vital importance. Suspension stability is essential to ensure that the particles to stay in suspension, and maintain constant particle size.

Temperature-dependent GISAXS studies on thin films

Temperature-dependent GISAXS studies on thin films

The temperature-induced decomposition of a thin film structure has been studied using the SAXSpoint system with the new temperature-controlled GISAXS stage.

An insight into the Structure of Copolymer Surfactants

An insight into the Structure of Copolymer Surfactants

The structure of inhomogeneous (core-shell) nanoparticles was studied with the SAXSpoint system. The internal structure of Pluronic P123 micelles in water was determined by calculating the radial electron density profile.

Collagen - A Validation Sample for SAXS Systems

Collagen - A Validation Sample for SAXS Systems

The performance of the SAXSpoint 2.0 system is evaluated by measurements of tendon collagen. SAXSpoint 2.0 produces data with excellent resolution in the entire angular range and delivers true 2D SWAXS images.

Understanding Filter Efficiency - Virus Removal in Depth Filtration

Understanding Filter Efficiency - Virus Removal in Depth Filtration

Zeta potential, as the indicator for surface charge, helps to predict and to tune the efficiency of filter materials.

Surface Modification of Kapton® Films

Surface Modification of Kapton® Films

The zeta potential is a valuable parameter to follow polymer surface modifications and to tailor-make biocompatible devices for medical applications.

Inner Surface Treatment of Haemodialysis Membranes

Inner Surface Treatment of Haemodialysis Membranes

The zeta potential measurement assists in the improvement of the biocompatibility of haemodialysis membranes.

Tuning of Solid Surface Properties by Self-Assembled Monolayers

Tuning of Solid Surface Properties by Self-Assembled Monolayers

The zeta potential measurement assists in tailoring the properties of technical and biomedical surfaces using self-assembled monolayers.

Correlating Viscosity and Particle Size Parameters determined by Small Angle X-Ray Scattering Studies of concentrated MAb Solutions

Correlating Viscosity and Particle Size Parameters determined by Small Angle X-Ray Scattering Studies of concentrated MAb Solutions

Monoclonal antibodies (MAb) solutions are a major class of biopharmaceuticals with various applications. However, challenges like a high viscosity at the required MAb concentrations need to be addressed at an early development stage.

Studying the Effect of Tear Fluid on Contact Lenses

Studying the Effect of Tear Fluid on Contact Lenses

The zeta potential indicates changes in the surface chemistry of contact lenses upon wearing and is thus suited to study biocompatible surface coatings.

Size and shape of gold nanoparticles in toluene via SAXS

Size and shape of gold nanoparticles in toluene via SAXS

A solution of colloidal gold nanoparticles was characterized for size and shape by the SAXSpace system.

优点

通过纳米结构的乳剂液滴研究运输过程动力学,确保成功地控制药物输送

当研究胶束作为载体提供活性成分和安定性的潜在应用时,必须通过研究胶束的内部结构进行补充。因为这些内部结构取决于组成,所以时间分辨 SAXS 实验可用于监测纳米结构乳剂液滴运输动力学的结构变化,比如维生素和酶等活性物质的吸收和释放。SAXSpace 能够满足成功的时间分辨 SAXS 实验的主要要求,即高强度和高分辨率,并且能在短测量时间内提供高质量数据。

研究水凝胶的弹性和力学特性

许多水凝胶被视为替代医学、再生医学和支架的潜在候选材料,或作为人体软组织的成长基体。最近的研究 (Discher et al., 2005; Moers et al., 2013) 显示,基体的弹性可以显著影响组织的体内平衡,这对组织再生非常重要。因此,测量生物基体的弹性和力学特性具有重要意义。安东帕的生物压痕测试仪可在液体中进行测试,且可在不同的加载模式下进行操作,帮助您轻松研究弹性模量和蠕变特性。可以研究玻尿酸的时间相关反应。

测量特性黏度和摩尔质量

可以根据制药用途改变玻尿酸的摩尔质量,以便定制其生物效应。体内的水凝胶半衰期很短;对于某些情况如整形手术,必须通过增加分子量来提高玻尿酸的稳定性。Lovis 2000 M/ME 微量黏度计测量玻尿酸溶液的黏度。可以通过玻尿酸和溶剂的相对黏度自动计算出其特性黏度。特性黏度提供的信息内容与摩尔质量相同。不过,也可根据 Mark-Houwink 方程计算出摩尔质量,然后在屏幕上直接读取。如果需要,可以进行自动零剪切速率推算来消除剪切速率的依赖性。

研究表面特性以确保移植物的生物相容性

表面电荷等表面特性可指示表面的生物相容性。蛋白质表面所需的高或低亲合力取决于使用的生物材料。在组织工程和再生医学中,蛋白质吸附会引起移植物的融合,而在其他情况下,蛋白质的高度粘附可能会导致血栓形成。在生理 pH 值条件下使用安东帕的 SurPASS 进行 Zeta 电位分析,可获取表面电荷信息和表面官能团的化学特性。zeta 电位的正负及大小可用于估测固体表面和溶解在周围水溶液中的带电种类之间的静电相互作用。