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Dynamic Light Scattering Instrument:
Litesizer DLS

  • +8
  • 360°
Model:
  • Particle characterization from the nanometer to the micrometer range
  • Particle size measurements via dynamic light scattering at three different measurement angles
  • Determination of zeta potential using patented cmPALS
  • Molecular mass and refractive index measurements
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Pick your country.
Europe
Austria
DE
Belgium
EN | FR
Croatia
EN
Czech Republic
CS
Denmark
EN
Finland
EN
France
FR
Germany
DE
Hungary
HU
Ireland
EN
Italy
IT
Liechtenstein
DE | FR | IT
Luxembourg
EN | FR
Netherlands
EN
Poland
PL
Slovakia
CS
Slovenia
EN
Spain
ES
Sweden
EN
Switzerland
DE | FR | IT
United Kingdom
EN
Asia-Pacific
Australia
EN
India
EN
Japan
JA
Malaysia
EN
New Zealand
EN
Philippines
EN
Singapore
EN
South Korea
EN | KO
Taiwan
ZH
Thailand
EN
Americas
Brazil
PT
Canada
EN | FR
Colombia
ES
Mexico
ES
United States
EN
Africa & Middle East
South Africa
EN
Turkey
TR
If you can't find your country in the list get a quote

The Litesizer DLS series characterizes nanoparticles and microparticles at the touch of a button. With these dynamic light scattering instruments, you can determine particles in dispersion and peptides or macromolecules in solution over a broad concentration range, which reduces your sample preparation time.

Key features

Benefit from the perfect angle choice – whatever your sample

Benefit from the perfect angle choice – whatever your sample

  • Ensure high resolution of different size populations via multi-angle particle sizing (MAPS)
  • Choose from three detection angles (side, back, or forward scattering) for optimal parameter settings
  • Manually select the most appropriate angle for your dynamic light scattering instrument or use automatic angle selection 
  • Benefit from the versatile back scattering angle, which is ideal for turbid samples as it reduces multiple scattering events and ensures optimal data quality
Rely on our cmPALS technique for zeta potential measurements

Rely on our cmPALS technique for zeta potential measurements

  • Perform zeta potential measurements via electrophoretic light scattering with Litesizer DLS 700 and Litesizer DLS 500
  • Conduct highly sensitive measurements at low sample concentrations (down to 0.1 mg/mL) with our patented cmPALS technique (European Patent 2 735 870) 
  • Enjoy shorter measuring times and minimal sample degradation with cmPALS
  • Get highly reproducible zeta potential measurements with our unique Ω-shaped capillary of the zeta potential cuvettes
Stay flexible with the particle concentration measurement mode

Stay flexible with the particle concentration measurement mode

  • Perform calibration-free particle concentration measurements of up to three different size populations present within one sample with Litesizer DLS 700
  • Use this mode based on single angle DLS or multi-angle particle sizing (MAPS) to ensure the applicability to monodisperse and polydisperse samples over a wide concentration range
Get continuous transmittance measurements for sample monitoring

Get continuous transmittance measurements for sample monitoring

  • Enjoy instant feedback on your sample – the dynamic light scattering instruments continuously measure transmittance
  • Take advantage of automatic optimization of measurement parameters (e.g., measurement angle, focus position, duration) 
  • Access information about the onset of sedimentation or aggregation within a series measurement
Determine refractive index with the same instrument

Determine refractive index with the same instrument

  • Measure refractive index of the solvent at the exact wavelength and temperature of DLS or ELS measurements (European Patent 3 023 770) with Litesizer DLS 700 and Litesizer DLS 500 
  • Ensure maximum accuracy of particle size and zeta potential results under all experimental conditions
  • Determine the refractive index within ±0.5 % with Litesizer DLS 700 and Litesizer DLS 500

 

Control your measurements with just a few clicks

Control your measurements with just a few clicks

  • Manage data with Kalliope, our user-friendly, particle sizing software
  • Know your input parameters, measurement signals, and results at a glance with our unique one-page workflow 
  • Quickly see your measurement results thanks to predefined standard reports and structured result overviews 
  • Take a deep dive into your data with an analysis function, Excel export, and customizable report templates
  • Comply with 21 CFR Part 11

Technical specifications

  Litesizer DLS 700 Litesizer DLS 500 Litesizer DLS 100
Particle size specifications
Measurement principle Dynamic Light Scattering (DLS)
Measuring range 0.3 nm to 10 μm (particle diameter)
Measurement angles 15°, 90°, 175°, Multi-angle particle sizing (MAPS) 15°, 90°, 175° 175°
Min. concentration 0.1 mg/mL (lysozyme)
lower than 0.00001 % (0.1 ppm, Latex 100 nm)    
0.1 mg/mL (lysozyme)
Max. concentration 50 % w/v (sample-dependent)
Min. sample volume 12 µL
Accuracy Better than +/-2 % on NIST traceable standards
Repeatability Better than +/-2 % on NIST traceable standards
Particle Concentration Specifications
Analysis model Mie Theory - -
Measuring range 108 - 1013 particles/mL (sample dependent) - -
Size limit 1 µm - -
Measurement angles 15°, 90°, 175°, Multi-angle particle sizing (MAPS) - -
Min. sample volume 12 µL - -
Accuracy +/- 10 % (sample dependent) - -
Repeatability +/- 5 % (sample dependent) - -
Zeta potential specifications
Measuring principle Electrophoretic Light Scattering (ELS) / cmPALS -
Measuring range >= +/-1000 mV -
Mobility range 10 -11 m²/V.s to 2 x 10 -7 m²/V.s -
Size range 3.8 nm to 100 µm (diameter) -
Min. sample concentration 0.1 mg/mL (lysozyme) -
Max. sample concentration 70 %w/v (sample-dependent) -
Max. sample conductivity 200 mS/cm -
Min. sample volume 50 µL (sample-viscosity-dependent) -
Accuracy Better than +/-10 % -
Repeatability +/-3 % -
Molecular mass specifications
Measuring principle Static Light Scattering (SLS) -
Measuring range (mass) 300 Da to 20 MDa -
Measuring range (particle size) Up to 40 nm (diameter) -
Measurement angle 90° -
Min. sample concentration 0.1 mg/mL (lysozyme) -
Accuracy +/-10 % -
Repeatability +/-5 % -
Transmittance specifications
Measuring range 0 % to 100 %
Min. sample volume 15 µL
Accuracy Better than +/-1 %
Refractive index specifications
Measuring range 1.28 to 1.50 -
Min. sample volume 1 mL -
Accuracy +/-0.5 % -
General specifications
Light source Semiconductor laser diode / 40 mW, 658 nm
Laser warm-up time 6 min
Temperature control range 0 °C to 90 °C
Ambient operating temperature 10 °C to 35 °C
Humidity Up to 80 % non-condensing
Dimensions (W, D, H) 460 mm, 485 mm, 135 mm
Weight Approx. 18 kg (40 lb) Approx. 16.3 kg (36 lb)

Standards

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ASTM

D4001 500, 700
E2490 100, 500, 700
E2865 500, 700
E3247 100, 500, 700

ISO

13099-2 500, 700
22412 100, 500, 700

U.S. Pharmacopoeia (USP)

432 500, 700
729 100, 500, 700
1153 500, 700
1430 100, 500, 700

Anton Paar Certified Service

The Anton Paar quality in service and support:
  • More than 350 manufacturer-certified technical experts worldwide
  • Qualified support in your local language
  • Protection for your investment throughout its lifecycle
  • 3-year warranty
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Consumables & Accessories

Consumables & Accessories

Accessories

Accessories

Not all items are purchasable online in specific countries.

To find out if you can purchase online from your location, check the online availability below.

Online price only | excl.incl. 0VAT

SLIDING FOOT - SELF ADHESIVE

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 253005
Product details
Self adhesive slider for the Litesizer DIA and dispersion unit feet.

O-RING FOR MEASUREMENT FRAME LIQUID FLOW DISPERSION UNIT

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 253103
Product details
O-ring 75 X 2.5 FKM for measuring cell glass frame in Liquid Flow measurement cell

SYRINGES 2 ml LUER (100 pcs.)

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 6771

SAMPLE FUNNEL SMALL

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 255106
Product details
A small sample funnel (max. 150 mL) Compatible with Dry Jet dispersion unit and Free Fall dispersion unit

SYRINGES 5 ml LUER (100 pcs.)

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 6772

SAMPLE FUNNEL LARGE

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 255107
Product details
A large sample funnel (max. 600 mL) Compatible with Dry Jet and with Free Fall dispersion unit

HOSE 2x4 SILICONE

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 51273

SAMPLE AND CLEANING KIT LITESIZER DIA

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 264542

O-RING 25x2 EPDM 70

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 74012

LOW-VOL. DISPOSABLE CUVETTE SET (Uvette)

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 175573
Product details
80 disposable low volume cuvettes (Eppendorf Uvette) incl. Litesizer lifter path length: 10 x 2 mm

VIAL 45 mL GLASS (100 Pcs.)

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 161744

OMEGA CUVETTE FOR ZETA & SIZE (10 pcs.)

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 225288

QUARTZ CUVETTE 12.5 x 12.5 x 45 mm

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 163390

BUFFER SOLUTION PH4.01 HAMILTON

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 12554

BUFFER SOLUTION PH7.00 HAMILTON

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 12556

PH STORAGE SOLUTION 500ML HAMILTON

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 12632

SUPPORTING PLATE

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 179343
Product details
for quartz low–volume cuvette

DISPOSABLE CUVETTE PS 10 x 10 x 45 mm

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 164435

DISPOSABLE CUVETTE LIDS 1 PACK OF 100 PIECES

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 243334

GLASS CUVETTE 12.5 x 12.5 x 45 mm

Compatible with:
Litesizer DLS 100 | 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 177389

BUFFER SOLUTION PH10.01 HAMILTON

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 46271

SYRINGE FILTER ANOTOP TYPE 25

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 163388

ZETA POTENTIAL CONTROL

Compatible with:
Litesizer DLS 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 227385
Product details
Pack of 6 syringes (3 ml each)

SYRINGE FILTER ANOTOP TYPE 10

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 163385

HOSE 1x2 SILICONE

Compatible with:
Litesizer DLS 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 67679

LOW VOLUME CUVETTE QUARTZ 45 µl 12.5 x 12.5 x 45 mm

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 163391

100 nm NIST TRACEABLE SIZE STANDARD

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 165155

220 nm NIST TRACEABLE STANDARD 0.002 %

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 182213

Dosing System

Compatible with:
Litesizer DLS 500
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Product details
  • Accessory for Litesizer 500
  • Automatically modifies the pH or adds solvents – saving time, and eliminating human error
  • Use pH ramp templates in the software to set up your experiments
  • Self-cleaning, no risk of sample carryover

More info

USB CABLE

Compatible with:
Litesizer DLS 100 | 500 | 700
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 94228