Medical samples & biomaterials, membranes

Opening up new channels for biomaterials engineering and research

Research on biomaterials, membranes, and medical samples requires high-precision tools which are reliable and intuitive to use. Whether you are investigating chemical processes, the behavior of particles, mechanical or elastic behavior or permeability, Anton Paar has a solution for you. 

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Anton Paar Products

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Anton Paar Bioindenter:
UNHT³ Bio

Automated Multipurpose Powder X-Ray Diffractometer:
XRDynamic 500

Benchtop Density Meter:
DMA

Capillary Flow Porometers for Through-Pores:
Porometer 3G

Capillary Flow Porometers for Through-Pores:
Porometer 3G micro

Capillary Flow Porometers for Through-Pores:
Porometer 3G z

Capillary Flow Porometers for Through-Pores:
Porometer 3G zH

Compact Raman Spectrometers:
Cora 5001

Abbemat Heavy Duty

Digital Heavy Duty Refractometer:
Abbemat

Digital Performance Refractometer:
Abbemat

Dynamic Image Analyzer:
Litesizer DIA 500

Dynamic Light Scattering Instrument:
Litesizer DLS

Dynamic Shear Rheometer Measuring Head:
DSR 502

Electrokinetic Analyzer for Solid Surface Analysis:
SurPASS 3 Eco

Electrokinetic Analyzer for Solid Surface Analysis:
SurPASS 3 Standard

Five-station gas pycnometers for true density:
PentaPyc and PentaFoam 5200e

Five-station gas pycnometers for true density:
PentaPyc and PentaFoam 5200e Foam

FTIR Spectrometer:
Lyza 7000

Fully Customizable Laboratory Automation Solution:
HTX

Gas Pycnometer for Semi-Solid and Solid Density:
Ultrapyc

Gas Sorption Analyzer:
QUADRASORB evo

High Vacuum Physisorption Analyzer:
Autosorb 6100

High Vacuum Physisorption/Chemisorption Analyzers:
autosorb iQ

High Vacuum Physisorption/Chemisorption Analyzers:
autosorb iQ C-AG

High Vacuum Physisorption/Chemisorption Analyzers:
autosorb iQ C-MP

High Vacuum Physisorption/Chemisorption Analyzers:
autosorb iQ C-XR

High-Pressure Volumetric Gas Sorption Analyzer:
iSorb

High-Pressure Volumetric Gas Sorption Analyzer:
iSorb HP1 100

High-Pressure Volumetric Gas Sorption Analyzer:
iSorb HP1 200

High-Pressure Volumetric Gas Sorption Analyzer:
iSorb HP2 100

High-Pressure Volumetric Gas Sorption Analyzer:
iSorb HP2 200

Inline Density Meter:
L-Dens 7400

Inline Density Meter:
L-Dens 7500

Inline Refractometer:
L-Rix

Mercury Intrusion Pore Size Analyzers:
PoreMaster

Mercury Intrusion Pore Size Analyzers:
PoreMaster 33

Mercury Intrusion Pore Size Analyzers:
PoreMaster 33GT

Mercury Intrusion Pore Size Analyzers:
PoreMaster 60

Mercury Intrusion Pore Size Analyzers:
PoreMaster 60GT

Micro Combi Tester:
MCT³

Microwave Digestion Platform:
Multiwave 5000

Microwave Digestion System:
Multiwave GO Plus

Microwave Reactor:
Monowave

Microwave Reactor:
Monowave 200

Microwave Reactor:
Monowave 400

Microwave Reactor:
Monowave 450

Modular Compact Rheometer:
MCR 702e MultiDrive

Modular Compact Rheometer:
MCR 702e Space MultiDrive

Modular Compact Rheometer:
MCR 72/92

Modular Compact Rheometer:
MCR 102e/302e/502e

Multiparameter Analyzing System:
Modulyzer Oil

Nano Scratch Tester:
NST³

Nanoindentation Tester:
NHT³

Pin-on-disk tribometer:
TRB³

Portable Density Meter:
DMA 35 Standard

Revetest Scratch Tester:
RST³

Rheometer Automation for High Sample Throughput and Complex Sample Handling:
HTR

Rolling-Ball Viscometer:
Lovis 2000 M/ME

Rotational Rheometer:
RheolabQC

SAXS/WAXS/BioSAXS System:
SAXSpace

SAXS/WAXS/GISAXS/USAXS/RheoSAXS Laboratory Beamline:
SAXSpoint 5.0

Ultra Nanoindentation Tester:
UNHT³

Vacuum and Flow Degasser:
FloVac

Vacuum Degasser:
XeriPrep

High Temperature Vacuum Tribometer

Vacuum Tribometer:
TRB V / THT V

Vapor Sorption Volumetric Gas Sorption Analyzer:
VSTAR

Vapor Sorption Volumetric Gas Sorption Analyzer:
VSTAR 2 Station

Vapor Sorption Volumetric Gas Sorption Analyzer:
VSTAR 2 Station Turbo

Vapor Sorption Volumetric Gas Sorption Analyzer:
VSTAR 4 Station

Vapor Sorption Volumetric Gas Sorption Analyzer:
VSTAR 4 Station Turbo

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Benefits

Differentiating between normal and pathological red blood cells

Anton Paar’s MCR rheometer is an excellent tool for monitoring the rheological characteristics of whole blood. At low shear stress, for example, red blood cells adhere to each other, aggregate, and form rouleaux. Using an MCR with a microscope accessory allows you to monitor changes in blood under various conditions through the microscope lens during the measurement. This combined information enables the correlation of the rheological properties of red blood cells to their aggregation state. Whole blood samples can be investigated according to the Recommendation of the International Committee for Standardization in Hematology.

Investigating the fouling of membranes and improving their biocompatibility

An economical and effective adsorbent for low-density lipoprotein (LDL) in blood is a dialysis membrane which is based on polysulfone with covalently bound heparin. However, problems inherent in the applicability of membranes in hemodialysis are surface-induced blood coagulation and membrane fouling due to irreversible protein adsorption. To improve the biocompatibility of these hemodialysis membranes, the inner surface of the membrane requires modification. A major challenge inherent to this process is the permanent coating with heparin. The grafting of reactive groups onto the polysulfone surface is one route to prepare the interface for the immobilization of such biologically active substances. The SurPASS electrokinetic analyzer is applied for analyzing the inner surface of such hollow-fiber membranes. Comparing the zeta potential of untreated and modified membranes reveals the efficiency of the surface treatment. The isoelectric point, which is obtained automatically, and the zeta potential values at higher pH are an indication that the grafting of reactive groups and the coating with heparin were successful.

Ensuring the safety of IV infusions

A common risk from intravenous infusions is contamination by particles that are not visible to the eye. To detect these unwanted particles and monitor the quality of IV infusions requires an analyzer such as Anton Paar’s Litesizer 500 which determines the particle size and particle size distribution of a solution quickly and from very small sample amounts (from 12 µL). The measurement meets the requirement of the US Pharmacopoeia for parenteral products which defines the size of droplets in emulsions and solutions to be infused or injected.

Assessing the level of trace elements in urine, blood, and hair

Evaluating trace element concentrations using, for example, ICP-MS/ICP-DRCMS and ETAAS requires sample solutions which are completely digested in order to minimize spectral and matrix interferences in the measurement. Microwave-assisted pressure digestion provides one such reliable method of sample preparation. Multiwave PRO, for example, decomposes body fluids and hair to produce high-quality samples in a short period of time. 

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