The moisturizing effect of the eye drops only lasts for a few seconds. | Analyze and precisely quantify the viscosity values of the methylcellulose solution in the eye drops at different temperatures, simulating real-life conditions (shear thinning effects during eye blinking and body temperature). | You can simulate the consistency of the eye drops by determining the viscosity values at different shear rates and temperatures. Knowing these values you can then adapt the portion of methylcellulose solution within the eye drops. | |
After approx. 6 months of storage the skin gel hardens in the tube. | Check the storage stability with a frequency sweep and thus observe and avoid separation of the two phases within the gel. | Fast and precise frequency sweeps can be performed with rheological oscillation tests. Predefined test templates enable you to characterize your gel within a few minutes with varying xanthan content. | - MCR 92
- MCR 102e, 302e, 502e
- MCR 702e
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The cough syrup does not stay on the spoon and flows through the digestive tract too fast (so the surface of the throat is not covered). | Determine single-point viscosity for quick quality checks or make multi-point analyses at a constant temperature with an increasing speed. | You can ensure the soothing effect and right viscosity of the cough syrup by using a single-point viscosity check or by studying the flow- or temperature-dependent behavior. For a more in-depth analysis of the flow behavior of the cough syrup, the mathematical model „shear thinning index“ can be used. | |
It is not possible to pump and squeeze ointments out of the packaging. During application on target body areas, good spreadability is not given. | Determine single-point viscosity for quick quality checks or perform multi-point analyses at a constant temperature with increasing speed/shear rate. | You can ensure perfect pumpability and spreadability of ointments by using a single-point viscosity check or by studying the flow behavior and the yield point. | |
The microemulsion separates into phases in heat (35 °C). | Analyze the temperature-dependent flow behavior at a constant speed/shear rate. | You can simulate the product’s behavior during storage at different temperatures and improve the formula accordingly. | |
After squeezing the ointment out of the tube the sample remains too thin. | Analyze the structural regeneration with a step test: 3 interval thixotropy test (3ITT). | With such a test you can simulate the real sample behavior during application. Interval 1 simulates the rest phase before processing. Interval 2 serves as a simulation of shearing during the application. Interval 3 describes the rest phase and structural regeneration after application (squeezing out of the tube/filling/pumping). | - RheolabQC
- MCR 72, 92
- MCR 102e, 302e, 502e
- MCR 702e
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Clinical nourishments cannot be swallowed easily. | Determine single-point viscosity for quick quality checks or perform multi-point analyses at a constant temperature with increasing speed/shear rate. | By analyzing the viscosity at low and high shear rates the viscosity of clinical nourishments at rest and during swallowing can be determined. Adding thickening agents to a low-viscosity fluid makes the fluid more viscous, which makes swallowing easier. | |
The pills disintegrate during the production process or storage. | Determine the cohesion strength of the powder which is used to press the pills. | You can figure out the critical parameters for the cohesion strength of your raw material and minimize the reject rate in the production process by using only powders with suitable properties and adjust the production parameters in a target-oriented way. | - MCR 102e, 302e, 502e
- MCR 702e
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The particulate raw material tends to segregate or demix during the production process. | Check the segregation and wall friction behavior of your granulate matter. | You can avoid negative influences on the effectiveness of the active pharmaceutical and problems in the production process due to changed powder flow behavior by adjusting the formulation of the raw material. | - MCR 102e, 302e, 502e
- MCR 702e
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The artificial joints show signs of wear very early after implantation. | Check the tribological behavior (friction, wear, lubrication) of the material combination used for the artificial joints. | You can investigate and optimize suitable material combinations and surface treatments to ensure the required long endurance of the artificial joints within a human body. | - MCR 102e, 302e, 502e
- MCR 702e
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The hand sanitizer (liquid and gel) just doesn’t feel right when applied on the hands. | Analyze the pumpability and spreadability with rotational- and how the product feels on the skin with oscillatory rheological measurements. | You can optimize the users’ experience by getting the rheological properties right, so the gel is easily dispensed, spreads nicely, and at the same time isn’t too liquid. | |
Upscaling production of vaccinations is difficult due to mixing problems of the components. | Find out the ideal processing and mixing parameters by analyzing rheological properties. | You can design the upscale from small lab-scale to large industrial processes by knowing the viscous properties. And you can also precisely control the quality during manufacturing. | |
When using methylcellulose the sample viscosity seems to change during production. | Measure the viscosity in dependence of an applied shear rate. | You can find the right processing parameters for each solution and concentration for maximum throughput without loss of material. | - RheolabQC
- MCR 92
- MCR 102e, 302e, 502e
- MCR 702e
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Applying dental filling composites in a patients’ tooth is difficult due to their shear thickening behavior during the filling process. | Analyze the cross-linking process and setting of composites. | You can guarantee unchanging behavior for easy use and application of dental filling composites. | - MCR 102e, 302e, 502e
- MCR 702e
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The environmental humidity renders the powder processing (e.g. for tableting) in the factory difficult. | Measure the impact of humidity on powder flow and other powder characteristics. | You can optimize the environment and processing parameters and thereby avoid expensive down-time during manufacturing. | |
