Medical samples & biomaterials, membranes
Opening up new channels for biomaterials engineering and research
Research on biomaterials, membranes, and medical samples requires high-precision tools which are reliable and intuitive to use. Whether you are investigating chemical processes, the behavior of particles, mechanical or elastic behavior or permeability, Anton Paar has a solution for you.
Anton Paar Products
MCR 703 MultiDrive
MCR 703 Space MultiDrive
XRDynamic 500
HTR 7000
Abbemat Essential 3001
Abbemat Essential 3101
Abbemat Essential 3201
UNHT³ Bio
Porometer 3G
Porometer 3G micro
Porometer 3G z
Porometer 3G zH
DMA 6002 Sound Velocity
Cora 5001 Direct Pharma
Cora 5001 Direct Standard
Cora 5001 Fiber Pharma
Cora 5001 Fiber Process Monitoring
Cora 5001 Fiber Standard
Litesizer DIA 100
Litesizer DIA 500
Litesizer DIA 700
Litesizer DLS 101
Litesizer DLS 501
Litesizer DLS 701
MCR 703 MultiDrive
DSR 502
SurPASS 3 Eco
SurPASS 3 Standard
MCR
Lyza 3000
Lyza 7000
Ultrapyc
Ultrapyc 7000
Ultrapyc 7000 Micro
Autosorb
Autosorb 6100
Autosorb 6200
Autosorb 6300
iSorb
iSorb HP1 100
iSorb HP1 200
iSorb HP2 100
iSorb HP2 200
L-Dens 7400
L-Dens 7500
L-Rix
Step
PoreMaster
PoreMaster 33
PoreMaster 60
MCT³
Multiwave
Multiwave GO Plus
Monowave
Monowave 200
Monowave 400
Monowave 450
DMA 4002
DMA 5002
DMA 6002
NST³
NHT³
TRB³
DMA 35 Standard
RST
MCR Rheometer + Cora 5001
RheolabQC
SAXSpoint 500
SAXSpoint 700
SAXSpace
UNHT³
TRB V / THT V
Differentiating between normal and pathological red blood cells
Anton Paar’s MCR rheometer is an excellent tool for monitoring the rheological characteristics of whole blood. At low shear stress, for example, red blood cells adhere to each other, aggregate, and form rouleaux. Using an MCR with a microscope accessory allows you to monitor changes in blood under various conditions through the microscope lens during the measurement. This combined information enables the correlation of the rheological properties of red blood cells to their aggregation state. Whole blood samples can be investigated according to the Recommendation of the International Committee for Standardization in Hematology.
Investigating the fouling of membranes and improving their biocompatibility
An economical and effective adsorbent for low-density lipoprotein (LDL) in blood is a dialysis membrane which is based on polysulfone with covalently bound heparin. However, problems inherent in the applicability of membranes in hemodialysis are surface-induced blood coagulation and membrane fouling due to irreversible protein adsorption. To improve the biocompatibility of these hemodialysis membranes, the inner surface of the membrane requires modification. A major challenge inherent to this process is the permanent coating with heparin. The grafting of reactive groups onto the polysulfone surface is one route to prepare the interface for the immobilization of such biologically active substances. The SurPASS electrokinetic analyzer is applied for analyzing the inner surface of such hollow-fiber membranes. Comparing the zeta potential of untreated and modified membranes reveals the efficiency of the surface treatment. The isoelectric point, which is obtained automatically, and the zeta potential values at higher pH are an indication that the grafting of reactive groups and the coating with heparin were successful.
Ensuring the safety of IV infusions
A common risk from intravenous infusions is contamination by particles that are not visible to the eye. To detect these unwanted particles and monitor the quality of IV infusions requires an analyzer such as Anton Paar’s Litesizer 500 which determines the particle size and particle size distribution of a solution quickly and from very small sample amounts (from 12 µL). The measurement meets the requirement of the US Pharmacopoeia for parenteral products which defines the size of droplets in emulsions and solutions to be infused or injected.
Assessing the level of trace elements in urine, blood, and hair
Evaluating trace element concentrations using, for example, ICP-MS/ICP-DRCMS and ETAAS requires sample solutions which are completely digested in order to minimize spectral and matrix interferences in the measurement. Microwave-assisted pressure digestion provides one such reliable method of sample preparation. Multiwave PRO, for example, decomposes body fluids and hair to produce high-quality samples in a short period of time.
