This is a required field.
Invalid
Part number
Error in validation!

Microwave Reactor with In-Situ Raman Spectroscopy:
Monowave 400 R

  • +3
  • Obtain real-time information about the chemical composition of pressurized reactions
  • Use precise time-temperature profiles to get deep insights into reaction behavior
  • No cleaning, no sample preparation, no cross-contamination

Combine Monowave 400 R with the Cora 5001 Raman spectrometer to receive a spectrum of information out of a former black box. Anton Paar combines two powerful techniques for synthetic chemistry – the microwave reactor Monowave 400 R delivers high-speed chemical reactions and the Raman analyzer Cora 5001 adds molecular spectroscopy for their characterization.

Gain a better understanding of reaction mechanisms and kinetics by combining precise temperature profiles with real-time information about the chemical composition of a reaction mixture. Optimize reaction conditions based on deeper insights, such as the influence of parameters, the role of different reagents, or detection of the ideal end point of a reaction.

Key features

Study chemical reactions under unprecedented reaction conditions

Study chemical reactions under unprecedented reaction conditions

Monowave 400 R provides the full range of operational parameters with temperatures of up to 300 °C and pressures of up to 30 bar. The Cora 5001 Raman analyzer performs time series measurements with adjustable intervals and exposure times during reactions, directly inside the reaction vial. The microwave reactor and the Raman spectrometer are connected via a special fiber-optic Raman probe.

Real-time in-situ reaction monitoring for a deeper understanding of reaction mechanisms

Real-time in-situ reaction monitoring for a deeper understanding of reaction mechanisms

Raman spectroscopy provides direct identification of functional groups and quantitative information about the composition of a reaction mixture. Detect non-isolable intermediates or short lifetime transitional states with time-resolved measurements for a deeper understanding of reaction mechanisms.

Applications include:

  • Identification of reactive intermediates
  • Elucidation of reaction mechanisms
  • Investigation of reaction kinetics
  • Monitoring of byproduct formation
  • Optimization of reaction conditions
Like a new probe every time with contactless measurement

Like a new probe every time with contactless measurement

The Raman probe employs a scattering method and can therefore be operated through the wall of the borosilicate glass vial for direct monitoring of the chemical composition of pressurized reactions. You can investigate various scales from 2 mL to 20 mL as the focus of the laser beam can be positioned optimally for both sizes of reaction vessels available with Monowave 400 R. With contactless measurement there is no cross-contamination, you have a free choice of reactants, and have no cleaning efforts between experiments.

Precise temperature control for perfect repeatability of the reaction course

Precise temperature control for perfect repeatability of the reaction course

Using microwaves for heating has a number of advantages: they heat up the reaction mixture directly inside the reaction vial without heating the surroundings. Unlike conventional heating sources, microwave heating can be turned on and off instantly, giving you complete control of the heating. Monowave 400 R uses these advantages to provide efficient heating at any scale for any solvent, with unmatched speed. The instrument’s software controller not only prevents temperature overshoots, but also facilitates cleaner conversions by exactly matching the desired temperature program. This allows you to accelerate chemical reactions and achieve reaction temperatures far above the boiling point of the used solvent.

Safe and reliable operation

Safe and reliable operation

Monowave 400 R is equipped with multiple interlock systems so that the user is safe from microwave and laser radiation. Both devices can be activated only if the swiveling cover of Monowave 400 R is closed. The combined setup fulfills the accessible exposure limits (AEL) of laser class 1.

Technical specifications

Anton Paar Certified Service

The Anton Paar quality in service and support:
  • More than 350 manufacturer-certified technical experts worldwide
  • Qualified support in your local language
  • Protection for your investment throughout its lifecycle
  • 3-year warranty
Learn more

Documents

Similar products

Consumables & Accessories

Consumables & Accessories

Accessories

Accessories

Not all items are purchasable online in specific countries.

To find out if you can purchase online from your location, check the online availability below.

REACTION VESSEL C30 WIDE NECK ASSEMBLED

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 173574
Product details
Single 30 mL wide neck silicon carbide vessel with wide neck with one Snap Cap Wide Neck and one corresponding PTFE Septum Wide Neck. Operation Volume 6-20 mL. 3 Note: For opening of the C30 Wide Neck vessel the use of the Decapper Wide Neck Vessels (Mat. No. 161692) is required.

CAVITY COLLAR

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 83212

FILTER DISC D14,8

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 84294
Product details
Small sintered metal filter inserted at the screw opening of the spill bin (83740). Shows fire retardant properties against escaping hot solvent vapors in case of a vial rupture.

CAVITY INSERT

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 88998

RUBY THERMOMETER

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 89047
Product details
Immersing fiber optic probe for accurate measurement of the internal reaction temperature, the operation range is 30 to 300 °C. Optional accessory for Monowave 200, Monowave 400, and Monowave 450. Included: 1 pcs. silicone septum for Ruby Thermometer (20 pcs.), 1 pcs. immersion tube for Ruby Thermometer, 1 pcs. holder for Ruby Therm Not included: PTFE Septum Wide Neck, Immersion Tube short for G30 Wide Neck Note: cannot be used with Monowave 100! Glass and quartz parts as well as complete reaction vessels are not covered by standard warranty.

MONOWAVE CONSUMABLES SET STANDARD

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 93537
Product details
Set of consumables, applicable for Monowave 200, Monowave 400, and Monowave 450, containing: Entry Qty. Mat.No. Item 1 1 pcs. 82724 Reaction Vial G10 (100 pcs) 2 1 pcs. 82723 Reaction Vial G30 (20 pcs) 3 1 pcs. 83214 Snap Cap (20 pcs) 4 5 pcs. 88883 Silicone Septum (20 pcs) 5 10 pcs. 89088 Stir bar 10x3 mm (10 pcs) 6 2 pcs. 165242 Stir Bar oval 15x6mm (10 pcs) 7 1 pcs. 89296 Rack 40 8 1 pcs. 23609 Rack 24 Note: not suitable for Monowave 100! Glass and quartz parts as well as complete reaction vessels are not covered by standard warranty.

CONSUMABLES SET MONOWAVE 450 Set of consumables, especially for Monowave 450, but also

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 165856
Product details
applicable to Monowave 400, containing: Entry Qty. Mat.No. Item 1 2 pcs 161723 Reaction Vial G30 Wide Neck (10 pcs). 2 2 pcs 161724 Snap Cap G30 Wide neck assembled (10 pcs). 3 2 pcs 161728 PTFE Septum Wide Neck (50 pcs.). 4 2 pcs 165242 Stir Bar oval 15x6mm (10 pcs.). 5 1 pc. 23609 Rack 24 6 1 pc. 161692 vial wide neck decapper Note: not suitable for Monowave 100 and Monowave 200 Glass and quartz parts as well as complete reaction vessels are not covered by the standard warranty.

TEST TUBE RACK 50 mL / 24 POSITIONS

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 23609
The ruby thermometer consists of a ruby crystal which is periodically excited by blinking light. The decay time of the luminescence is temperature-dependent and correlates with the temperature around the crystal.

Ruby Thermometer

More info
Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months

REACTION VIAL WIDE NECK DECAPPER

Online price only | excl.incl. 0VAT
Delivery time: %1$s – %2$s working days %1$s – %2$s weeks %1$s – %2$s months
Part number: 161692
Product details
Optional simple tool for easy decapping of the G30 Wide Neck reaction vials.