Laser Diffraction Particle Size Analyzer:
Litesizer DIF
- Measurement of samples from 0.1 µm to 2,500 µm
- Switching between liquid and dry dispersion in just one move
- Kalliope software: No training required, dedicated QC mode
- Reliable results even in harsh environments
- Compatible with Liquid Flow Imaging dispersion unit
The Litesizer DIF series offers advanced particle sizing from 10 nm to 3.5 mm, drawing on nearly 60 years of laser diffraction expertise. This laser diffraction particle size analyzer has a best-in-class optical setup featuring powerful 10 mW and 25 mW lasers and the widest range on the market of detected diffraction angles from 0.01° to 170°. The Kalliope software simplifies particle sizing, requiring no extensive training – measurements start with just three clicks. The Quick-Click system allows easy switching between dispersion units, minimizing errors. Safety features for both liquid and dry dispersion ensure effortless, secure operation.
The robust metal housing and the isolated optical bench deliver reliability everywhere: from harsh environments, to high-tech laboratories.
Fueled by our pioneering legacy, this is next-generation laser diffraction technology – the Litesizer DIF series: From First to Best.
Key features
Particle sizing in any environment
Anton Paar's Litesizer DIF is suitable for heavy industries. It is made of high-quality components inside and out. Sturdy metal housing encases durable optical elements. Litesizer DIF is built to endure harsh environments: No dust or powder can penetrate into the optical bench of the instrument, and the inside of the instrument is isolated from possible direct vibrations at the production site. All of this means savings on upkeep and repair costs.

Kalliope: The benchmark software for particle sizing
With Kalliope, users immediately know how to get started, via the one-page-only workflow (setting parameters, acquiring and working with results). Additionally, the QC mode offers consistent reliable measurement results by customizing user management and locking delicate settings. The instrument in QC mode gives simple feedback if your product is within your defined limits. This means results in just three clicks and less training for new users. In addition, a pharma option with data security functions, user management, and audit trails is included, making Kalliope compliant with the US FDA’s 21 CFR Part 11.

Efficient dispersion, maximum safety
Litesizer DIF's Quick-Click feature connects the dispersion units in just one move – no hassle with cables, tubes or pipes. The obscuration level indicator allows monitoring of the sample amount while adding it, ensuring the right amount from the start.
The Dry Jet dispersion unit has a suction check and built-in dust cover to minimize the risk of powder spread.
The Liquid Flow unit automatically checks for sufficient liquid before sonication, preventing overheating. A dedicated module with high chemical resistance is available for aggressive liquids.
The Liquid Flow Imaging unit combines laser diffraction and dynamic image analysis adding shape parameters of particles from 5 µm in size.

On quality, we lead the way
Litesizer DIF is the perfect tool for particle analysis due to its high-quality manufacturing. It features high-grade hardware, empowering the instrument to collect superior raw data. This laser diffraction particle size analyzer enables users to measure a broad range of samples, covering particle sizes from 0.01 µm to 3,500 µm, all with a single analyzer – without the need for additional investment.

Less investment, saved bench space – compatibility across the board
Compatibility of dispersion units between Anton Paar’s Litesizer DIA and Litesizer DIF instruments reduces investment costs and lab space usage. On top of that, all Litesizer instruments can be operated using a single PC with the Kalliope software installed.

Specifications
Litesizer DIF 500 | Litesizer DIF 300 | Litesizer DIF 100 | |
---|---|---|---|
Measurement principle | Laser Diffraction (Mie and Fraunhofer scattering) | ||
Measurement range | 0.01 μm - 3,500 μm | 0.1 μm - 2,500 μm | 0.1 μm - 1,000 μm |
Size classes | 144 (user adjustable) | 114 (user adjustable) | 104 (user adjustable) |
Accuracy * | better than ± 0.5 % variation*** | ||
Repeatability | better than ± 0.5 % variation*** | ||
Reproducibility** | better than ± 1 % variation*** | ||
Possible measurement duration | <10 sec | ||
Data acquisition rate | 16 kHz | ||
Light source 1 | |||
Type | Fiber coupled laser diode | ||
Optical arrangement | Reverse Fourier | ||
Wavelength | 830 nm, infrared | ||
Power | 10 mW | ||
Laser Class | Class 1 (IEC60825-1) | ||
Light source 2 | Litesizer DIF 500 | - | |
Type | Laser diode | - | |
Optical arrangement | Tilted relative to IR laser | - | |
Wavelength | 450 nm, blue | - | |
Power | 25 mW | - | |
Laser Class | Class 1 (IEC60825-1) | - | |
Detectors | |||
Type | Log-spaced photo diode array and single diodes for side and back-scattering | ||
Angular range | 0.01° - 170° | 0.01° - 155° | |
Focal length | 300 mm | ||
Alignment | Automatic | ||
Instrument data | |||
Instrument dimensions**** | 400 mm x 790 mm x 290 mm (H x W x D) | ||
Instrument weight**** | 42.3 kg (93.2 lb) | ||
Power supply | 100 V to 240 V ±10 %, 50/60 Hz |
Trademarks:
• Kalliope (EU: 012709391), (UK: UK00912709391)
• Litesizer (EU: 011695491), (UK: UK00911695491)
* Defined for a monomodal latex standard and accounting for manufacturer's uncertainty of standard size.
** Defined for D50 of a polydisperse standard.
*** Sample and preparation dependent. Defined for liquid dispersion measurements.
**** Without PC and dispersion uni
Standards
CFR
Standards
CFR
Standards
CFR
Anton Paar Certified Service
- More than 350 manufacturer-certified technical experts worldwide
- Qualified support in your local language
- Protection for your investment throughout its lifecycle
- 3-year warranty
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If you do not find the item you require, please contact your Anton Paar sales representative.

Automation Option for Particle Analysis:
Litesizer Autosampler
Litesizer DIF 100 | 300 | 500
- Measure liquid and dry samples
- Measure up to 60 samples per run
- Add and prioritize samples even during an active run
- Ensure safety with cobot functionality

MEASUREMENT WINDOW FOR LIQUID FLOW DISPERSION UNIT
Litesizer DIF 100 | 300

Accessory for Litesizer DIA and DIF:
Dispersion Unit Liquid Flow
Litesizer DIF 500
- Dispersion of samples using a carrier liquid
- Automated filling, draining, and rinsing of the dispersion liquid
- Prevention of overheating with automatic recognition of liquid
- Dedicated version with high chemical resistance available for handling aggressive liquids
- Available for the Litesizer DIA and Litesizer DIF series

Accessory for Litesizer DIA and DIF:
Dispersion Unit Dry Jet
Litesizer DIF 500
- Dispersion of samples using pressurized air
- Automation for optimal sample feeding rate
- Prevention of toxic or explosive sample spread with safety cover
- Containment of dangerous samples with automatic suction check
- Available for the Litesizer DIA and Litesizer DIF series

Accessory for Litesizer DIA and DIF:
Dispersion Unit Liquid Flow Imaging
Litesizer DIF 500
- Combination of laser diffraction and dynamic image analysis
- Measurement of shape parameters from 5 µm to 2,500 µm
- Dispersion of samples using a carrier liquid
- Inclusion of all features of the liquid flow dispersion unit
- Only available for the Litesizer DIF series

Particle Analysis Software:
Kalliope
Litesizer DIF 500
- Particle analysis software for all Litesizer instruments
- Particle measurement start in just three clicks
- One-page workflow user interface
- Live monitoring of measurement results, analysis function
