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Rheology of Thickeners in Pharmaceuticals: Xanthan Gum

Introduction

Viscosity-increasing ingredients such as xanthan gum are widely used in complex products such as pharmaceuticals, creams, health-care products, food ingredients and dietary supplements. Their use is regulated by standards, such as the Pharmacopoeia (e.g. United States Pharmacopoeia and the European Pharmacopoeia) [1] [2] [3] [4]. Although the applications of these ingredients are diverse, absolute and trustworthy rheological data are constantly required for the production and quality management of such products. 

[1] General Chapter <912> Rotational Rheometer Meth-ods, US Pharmacopeial Convention

[2] USP-NF Monographs: Xanthan, US Pharmacopeial Convention

[3] 20210 Viscosity - Rotating Viscometer Method, European Pharmacopoeia: 01/2008

[4] 1277 Xanthan, European Pharmacopoeia: 04/2009

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