DMA 35 in Use for Safety in Hemodialysis

Hemodialysis needs large amounts of correctly prepared dialysate solution. Density measurements with the portable digital density meter DMA 35 provide additional quality control parameters to ensure the correct dialysate concentration parallel to conductivity values.


Hemodialysis (HD) is the commonest form of kidney replacement therapy in the world. The primary goal is to restore the intracellular and extracellular fluid environment that is characteristic of normal kidney function. The required dialysate solution or dialysate fluid mainly consists of purified water, K+, Na+, Mg2+, Ca2+ and HCO3-, but also glucose and an acid might be added.

Dialysate composition strongly influences the exchanges of electrolytes between blood and dialysate, restores body electrolyte concentrations and acid-base equilibrium. Therefore, it is a key element for effective and safe hemodialysis. 

To produce a dialysate fluid, purified water is typically mixed with dialysate powder or dialysate concentrate.

The correct concentration of the prepared solution is commonly tested with conductivity measurement.

No measurement method guarantees 100 % safety. Unfortunately, in hemodialysis, an incorrectly prepared dialysis solution is coupled with tremendous health risks. An additional, independent parameter, parallel to conductivity measurements, ensures the correct concentration of dialysate solutions. The solution’s density provides this additional quality control information and considers also non-ionic components in contrast to conductivity measurements.

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