Density measurement for inhalant supervision from aerosol cans

Hydrofluoroalkanes (HFAs) are used for pharmaceutical and medicinal purposes, especially as aerosol propellants in inhalers. With a suitable medical excipient added, HFAs can serve as drugs for the treatment of human respiratory diseases. Density measurement allows for determining the correct compositions.

The density difference between HFA-227 with 0.3% and 0.8% excipient, approximately 0.002 g/cm3, indicates that it is possible to distinguish between the varying concentrations using a density meter equipped with an aerosol adapter.

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