Pharmaceuticals and Cosmetics | Quantification of an Active Pharmaceutical Ingredient in Excipient Using Lyza 7000 and Pike EasiDiff

Powders containing low analyte concentrations can be analyzed with Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) with minimal sample preparation. Lyza 7000 equipped with a DRIFTS accessory allows the reliable quantification of the active pharmaceutical ingredient (API) acetaminophen in a corn starch excipient matrix.

Reliable analytical techniques are essential for quality control in pharmaceutical formulations, especially when active ingredients are present in low concentrations. Fourier Transform Infrared (FTIR) spectroscopy, and specifically its diffuse reflectance variant (DRIFTS), offers a rapid, non-destructive method for analyzing powdered samples with minimal preparation. 

This report presents the quantification of acetaminophen, a common active pharmaceutical ingredient (API), in a corn starch excipient matrix using DRIFTS.

Get the document

To receive this document please enter your email below.

Loading...

Error