Infused Excellence: Perfecting Cannabinoid Nanoemul-sions using Dynamic and Electrophoretic Light Scattering

Cannabinoids are a class of chemicals which are the active ingredients extracted from cannabis plants: Cannabis sativa. Cannabidiol (CBD) and d9-tetrahydrocanna-binol (THC) are the most widely known and studied. Lesser-known compounds include cannabigerol (CBG), cannabichromene (CBC), and cannabinol (CBN). These are used less frequently but still appear in consumer products.
D9-THC and its close variants, d8-THC, d10-THC, and THCV, are all widely known to be psychoactive cannabinoids affecting people’s perceptions. Increasing evidence suggests CBD, CBG, CBN, and CBC show that these compounds exhibit positive effects as well. These cannabinoids exhibit potential anti-inflammatory, analgesic, calming, appetite-stimulating and neuroprotective properties.
The improvements in cannabinoid extraction over recent years have led to more efficient, sustainable, and precise methods. These advancements not only ensure better product quality and consistency but also cater to a growing demand for specific cannabinoids and terpene pro-files. As research and technology continued to evolve new products and formulations were developed.
The particle size significantly influences how quickly and efficiently a substance is absorbed into the bloodstream. Smaller particles supply a larger surface area compared to larger particles. This increased surface area facilitates the dissolution of the drug in the gastrointestinal tract (for oral administration) allowing the drug to enter the blood-stream more rapidly.
Nanoparticles or micronized drugs (with very small particle sizes) are generally absorbed more quickly by the body because they can more easily penetrate cells or mucous membranes. Nano- or microemulsions are used to enhance the bioavailability of poorly soluble or poorly absorbable substances.