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Multiparameter Measurement System:
Turbidity Measurement System

  • +4
  • One filling cycle, 2 key parameters: density and turbidity
  • Turbidity: proven ratio method, analyzing particles of any size
  • Automatic filling possibilities with a minimum sample volume
  • Full traceability including user-management and audit trail
  • DMA 4501, Xsample 520, Haze 3001
Turbidity Measurement System

Density, specific gravity and turbidity measurement from a single filling cycle – the Turbidity Measurement System combines two key parameters for injectables, infusions, vaccines, biopharmaceuticals, and liquid formulations. Proven density measurement and a robust, fully-enclosed turbidity measuring module require minimal sample volumes and offer various filling possibilities, as well as accurate temperature control to obtain the best result possible in the shortest time. Superior software features included for regulated industries ensure complete traceability.

Key features

Your 2 key parameters from a single sample

Most liquid pharmaceutical formulations, chemicals, or flavor and fragrance compounds have to be clear. Opalescence-inducing particles indicate contamination or even an unsafe product. In many biotechnological applications, turbidity changes are a parameter to monitor filtration, cleaning processes and factors like protein aggregation, whilst also measuring the sample’s density with the superior DMA.
The turbidity measurement system combines the measurement of these two parameters with one sample filling. The measurement is controlled from the density meter and results are instantly combined in one data set, avoiding compilation error. 
 

Minimal sample volume required

Never waste precious sample liquid again when filling standard measuring cuvettes and high-volume glass pycnometers or hydrometers. The Turbidity Measurement System facilitates reliable measurements with as little as 3 mL of sample volume for a single turbidity measurement when injected directly at the Haze 3001 module, or as little as 5 mL for a combined density and turbidity measurement.

Degree of automation based on your requirements

There is a filling solution for each requirement – from sample throughput to sample properties or necessary safety measures. Fill and measure a day’s workload of samples with a multi-sample changer, freeing up time for other laboratory tasks. Properly fill and clean hazardous samples with a single sample changer to safely handle dangerous substances like aggressive chemicals or biologically active pharmaceuticals. For a quick determination of a single measuring parameter, simply fill the specific measuring module directly with a syringe to minimize sample consumption.

No complex handling of cuvettes for turbidity measurements

Maintaining the glass cuvettes for a regular turbidity meter can be inconvenient. Thorough cleaning, avoiding surface scratches, regular calibrations, and marking for best orientation in the measuring cell, as well as wiping the cuvettes with silicone oil to minimize light distortion, normally need to be performed for continuously-accurate measurements. However, the robustly-built, completely-enclosed measuring cell and setup of the Haze 3001 turbidity module eliminate all these inconveniences. Simple flow-through filling is all that’s needed.

Accurate temperature control safeguards precision

Sample temperature is a factor that significantly affects density and turbidity values. The Turbidity Measurement System’s measuring modules have best-in-class Peltier-based temperature control, allowing for fast temperature equilibration of the sample, as well as perfect control of the measuring conditions. Continuous reproducible results are guaranteed.

Complete traceability and data handling

In all regulated industries following GMP guidelines, all actions on laboratory instruments need to be documented. Superior compliance features like user management, audit trail, and electronic signature/review & approval processes eliminate any uncertainties about your measured results. Control your instruments directly from your computer via a network connection and use our lab execution software, AP Connect, to collect, review, and organize your measurement data. Industry-specific instrument qualification packages and competent service minimize the time it takes to integrate your Turbidity Measurement System in your daily workflow and operational activities.

Standards

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European Pharmacopoeia (Ph. Eur.)

2.2.1. Clarity and degree of opalescence of liquids
2.2.5. Relative density

US Pharmacopoeia (USP)

841 - Specific Gravity
855 - Nephelometry, Turbidimetry, and Visual Comparison

Japanese Pharmacopoeia (JP)

2.56 Determination of Specific Gravity and Density (4. Measurement using an oscillator-type density meter)

Anton Paar Certified Service

The Anton Paar quality in service and support:
  • More than 350 manufacturer-certified technical experts worldwide
  • Qualified support in your local language
  • Protection for your investment throughout its lifecycle
  • 3-year warranty
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