The fate of proteins at surfaces: How decisive is the zeta potential?
The interaction of proteins with material surfaces is ubiquitous in our daily life. Depending on the material's application and the corresponding protein, surface adsorption may be highly welcome or undesired. Electrostatic attraction or repulsion often dominate the protein-surface interacton. The zeta potential, which represents the charge of both, the protein and the material surface, lets us directly determine the type and magnitude of electrostatic interaction.
Join this webinar and learn how zeta potential analyses of proteins (by electrophoretic light scattering) and material surfaces of various kind (by streaming potential measurement) helps to predict the fate of proteins at surfaces. Applications include
- the biocompatibility of implants,
- the equipment of material surfaces with antiadhesive coatings, or
- the selection of appropriate conditions to prevent adsorptive loss in formulation transport and storage.
Thomas Luxbacher received his PhD degree in Technical Chemistry at Graz University of Technology and looks back at almost 20 years of experience as a product manager in different areas. He is currently the principal scientist for surface charge and zeta potential at Anton Paar GmbH.
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