The fate of proteins at surfaces: How decisive is the zeta potential?
The interaction of proteins with material surfaces is ubiquitous in our daily life. Depending on the material's application and the corresponding protein, surface adsorption may be highly welcome or undesired. Electrostatic attraction or repulsion often dominate the protein-surface interacton. The zeta potential, which represents the charge of both, the protein and the material surface, lets us directly determine the type and magnitude of electrostatic interaction.
Join this webinar and learn how zeta potential analyses of proteins (by electrophoretic light scattering) and material surfaces of various kind (by streaming potential measurement) helps to predict the fate of proteins at surfaces. Applications include
- the biocompatibility of implants,
- the equipment of material surfaces with antiadhesive coatings, or
- the selection of appropriate conditions to prevent adsorptive loss in formulation transport and storage.
Thomas Luxbacher is principal scientist for surface charge and zeta potential at Anton Paar. Prior to his present role, he was a product manager for surface zeta potential analyzers for more than 15 years. Before joining Anton Paar, Thomas gained experience in the semiconductor and automotive businesses. He received his MSc and PhD degrees in Physical Chemistry from Graz University of Technology.
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