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Modular Circular Polarimeter: MCP 5100/5300/5500

Polarimetry without limits

The MCP polarimeter series combines state-of-the-art technology, modern design, and high usability. Customer-specific configurations, like multiple wavelengths, provide the widest range of options to keep the polarimeter fit for the future. MCP 5100/5300/5500 is the perfect solution for measuring the optical rotation and determining the concentration or specific rotation of optically active substances for the pharmaceutical, cosmetic, and chemical industries, as well as for R&D. Its modern data management – fully compliant with 21 CFR Part 11 – provides data integrity – no matter whether the polarimeter is operated stand-alone, desktop-PC-controlled, or connected to the network.

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Key Features

External MCP desktop software, taking care of all data administration

External MCP desktop software, taking care of all data administration

The polarimeter is controlled by the external MCP desktop software. All interaction takes place on the connected PC. User group, system, and data administration will be performed by the computer, not by the instrument, so the time to qualify the instrument is immensely decreased. Lifetime data (measured data, audit trail, check, and adjustment) is automatically stored as raw data in the desktop database. This database can be backed up and restored on demand by customer IT processes.

Raw Data Viewer for data authenticity check

Raw Data Viewer for data authenticity check

The MCP polarimeter is connected to the network or PC via Anton Paar LIMS Bridge to collect or administrate data. The Anton Paar Raw Data Viewer provides the plausibility check, meaning that archived raw data can be loaded and regenerated from machine-readable into human-readable format for the verification process. Automatic checks verify the integrity of digitally signed data – in case of changes the file verification will be rejected.

Comprehensive qualification documentation

Comprehensive qualification documentation

With the Anton Paar Pharma Qualification Documentation, your new MCP polarimeter is integrated into your workflow within a short period of time. 

IQ/QO/PQ as well as a risk analysis and 21 CFR Part 11 checklist are provided. A local Anton Paar employee will carry out the instrument qualification together with you – this saves you time and money.

Modular concept to grow with your requirements

Modular concept to grow with your requirements

Your investment in an MCP polarimeter is secure, no matter which measurements you will face in the future. All MCP models can be upgraded, e.g. with additional wavelengths, air pump, or FillingCheck camera to meet new requirements. Up to eight spectral filters in the UV/VIS/NIR ranges can be added to the instrument right away or later on as a field upgrade.

Technical highlights for maximum reliability

Technical highlights for maximum reliability

The MCP polarimeters equipped with features for the highest traceability and reliability:

  • Wireless Toolmaster™ technology – automatic identification of sample cells and quartz control plates
  • FillingCheck™ – built-in camera to monitor real-time images of the filling process (optional for MCP 5100/5300)
  • Automatic Peltier temperature control – eliminates the need for a thermostatic water bath
  • LED light source – maintenance-free for 100,000 hours
  • Built-in air pump to discharge the sample from the cell, clean and dry the sample cell inside (optional for MCP 5100/5300)
  • Up to eight spectral filters in the UV/VIS/NIR ranges (optional)
Wide range of sample cells ready for your application

Wide range of sample cells ready for your application

A variety of sample cells available in different path lengths, materials, and filling options meet all your possible requirements. All MCP polarimeter sample cells come with wireless technology supporting the Toolmaster™ function. Cell type and master data are automatically transferred to the instrument. MCP automatically checks if the cell meets the selected method settings. Live temperature data is also transmitted to the instrument. 

Whatever the application, Anton Paar provides the suitable sample cell.

Technical Specifications

°OR at 589 nm
MCP 5100 MCP 5300 MCP 5500 MCP 5500 MW 325
Measuring scales °Optical Rotation, °Optical Rotation (cell-length corrected), °Specific Rotation, °Specific Rotation (cell-length corrected), % concentration (g/100 mL, g/L, g/100 cm³, kg/m³), °International Sugar scale (not temperature-compensated), mathematic functions and user-definable scales
Measuring range ± 89.9° ± 89.9° ± 89.9° ± 89.9°
Resolution 0.001° (0.0001° optional) 0.001° (0.0001° optional) 0.0001° 0.0001°
Accuracy* ± 0.0025° (± 0.0020° optional) ± 0.0020° < 0.0020° < 0.0020° (589 nm)
Repeatability ± 0.002° ± 0.002° ± 0.001° ± 0.001°
Response time 12 seconds 12 seconds 15 seconds 15 seconds
Wavelengths 589 nm and optionally up to eight wavelengths. Standard spectral wavelengths (365, 405, 436, 546, 578, 633, 880 nm), customer-specific wavelengths on request
Light source LED light source from 50 000 up to 100 000 hours lifetime for all wavelengths (325 nm to 880 nm)
Sensitivity Optical Density (OD) of 4.0 Optical Density (OD) of 4.0 at 589 nm
 
Temperature control and measurement
Sensor PT100 sensor for sample temperature measurement inside the cell or quartz control plate; wireless transfer to the instrument
Resolution 0.1 °C 0.01 °C 0.01 °C 0.01 °C
Accuracy** ± 0.1 °C ± 0.05 °C ± 0.03 °C ± 0.03 °C
Temperature control range*** 20 °C + 25 °C 
(optional 10 °C to 45 °C)
10 °C to 45 °C
 
Dimensions, power requirements, interfaces
Dimensions (L x W x H) 797 mm x 437 mm x 231 mm
Weight 33.5 kg
Power management Power-supply self-adapting to any mains voltage, 100 to 240 VAC, 50/60 Hz
Power consumption 185 VA
Interfaces 4 USB, RS232, Ethernet, VGA, CAN bus. Easy connection of keyboard, mouse, printer, bar code reader and networks.
 
Accessories
Sample cells ToolMaster™: Wireless automatic identification of sample cells via RFID, sample cell path length from 2.5 mm to 200 mm
Quartz control plates Automatic identification of the quartz control plate and automated wireless transfer or reference parameters into the instrument

* under physical standard conditions

** with Peltier module and Toolmaster™ sample cell (50/100/200 mm)

*** the temperature control at 10 °C is under physical standard conditions

Standards

A

AOAC 940.11
AOAC 926.14
AOAC 954.14
AOAC 926.18
AOAC 970.57
AOAC 930.36
AOAC 920.82
AOAC 926.11
AOAC 898.02
AOAC 925.33
AOAC 902.02
AOAC 975.43
AOAC 950.30
AOAC 950.29
AOAC 945.37
AOAC 925.35
AOAC 930.32
AOAC 986.19
AOAC 920.65
AOAC 945.55
AOAC 933.04
AOAC 965.31
AOAC 925.52
AOAC 896.01
AOAC 925.47
AOAC 896.02
AOAC 920.190
AOAC 920.184
AOAC 920.189
AOAC 920.188
AOAC 920.182
AOAC 920.139

P

Ph. Eur. 2.2.7 - Optical rotation

U

USP 781 - Optical rotation

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