Quality Control of Saline Solution

Abbemat refractometers from Anton Paar are valuable instruments for the precise analysis of concentration and purity of saline solutions.

Saline solution in medical applications

Saline solution is composed of sodium chloride and water in the ratio 1:1. In isotonic concentration it may be used as a vehicle for injectable pharmaceuticals as well as a flushing solution in medical applications. Other applications in medicine include its use as a nasal spray as well as intravenous infusion for volume substitution in emergencies. Further, an intravenous infusion of isotonic saline solution is used for salt replacement therapy after heavy salt loss, e.g. in case of heavy sweating or diarrhea. Isotonic saline solution is also used as a storage solution for medical items with high water content, like contact lenses.

Due to the highly sensitive applications of saline solutions, exact purity and quality control is essential in their production, as incorrect concentrations and impurity would have severe consequences when administered to the human body.

Monitoring concentration and purity of saline solutions with Abbemat refractometers

Salts, like sodium chloride, have a significant refractive index in aqueous solution that is proportional to the concentration. This makes the Abbemat refractometers ideal instruments to measure the concentration and the purity of saline solutions quickly and reliably in a variety of industries as no further processing of the sample is required. All Abbemat refractometers have the predefined method "Salinity NaCl" which directly converts the refractive index into the concentration of sodium chloride in water.

As the refractive index and therefore the sodium chloride concentration is dependent on the temperature, all Abbemat refractometers have an internal Peltier temperature control with an accuracy of at least 0.05 °C.

Learn more about the Abbemat Refractometers

Other relevant instruments

The density of salt solutions and mixtures can easily be measured with a density meter from Anton Paar.

Good to know

The Abbemat refractometers measure the refractive index of salt mixtures as well as the concentration of sodium chloride in water quickly and easily at high precision.